McKenna's Pharmacology for Nursing, 2e

979

Index

Corpus luteum, 596, 599 Corpus striatum, 372, 373 Corticosteroids, 536, 537 adults, 540 children, 540

Decimals, 53, 54 converting to and from fractions, 54 decimal places, 54 dividing, 55 multiplying, 54–55 rounding, 54 Decongestants, 842, 846–852 oral, 842, 847, 849–851 topical nasal, 842, 846–849 topical nasal steroids, 842, 847, 851–852 Degarelix, 212, 213 Delayed allergic reaction, 33, 34 Dendrites, 292, 293 Denominator, 53, 54 Depolarisation, 292, 294 Depolarising neuromuscular junction (NMJ), 432, 434 blockers, 437–439 adverse effects, 438 care considerations, 439 contraindications and cautions, 438 drug–drug interactions, 438 pharmacokinetics, 438 therapeutic actions and indications, 437–438 Depression, 316, 317 biogenic amine theory, 316, 317 drug therapy, 317 Dermal patch delivery systems, 504 Dermatological reactions, 31, 33–34 Desflurane, 420, 422 Desloratadine, 853, 854 Desmopressin, 521, 523, 530–533 Desogestrel, 607, 608, 611 Desvenlafaxine, 330–331 Devil’s claw, 613 Dexamethasone, 539, 542, 543, 954, 957 Dexamphetamine, 347 Dexchlorpheniramine, 852, 854 Dexmedetomidine, 313 Dextromethorphan, 842, 844, 845 Dextropropoxyphene, 401, 402 DHEA (dehydroepiandrosterone), 964 Di huang, 471, 964 Diabetes insipidus, 521, 530–532 Diabetes mellitus, 572, 573, 576–578 cultural blood glucose variations, 577 hyperglycaemia, 578 hypoglycaemia, 578 type I, 584–585 Diagnostic and Statistical Manual of Mental Disorders , 335 Diarrhoea, 916, 917 Diastole, 642, 643 Diazepam, 303, 305–307, 352, 354, 357, 359–360, 362, 386, 388, 389 Diazoxide, 666, 674 DIC (disseminated intravascular coagulation), 760 Diclofenac, 247, 957

Digestive enzymes, 896, 912–913 adverse effects, 912 care considerations, 913 contraindications and cautions, 912 dysfunction, 897 pharmacokinetics, 912 therapeutic actions and indications, 912 Digoxin, 681, 685–692, 703, 707–708 antidote, 681, 688 chronic antiarrhythmic therapy, 709–711 inadequate absorption, 690–692 toxicity, 688 Digoxin immune fab, 688 Diltiazem, 657, 665, 671–672, 696, 703, 706–707, 714, 716, 724 Dimenhydrinate, 853, 854 Dinoprostone, 606, 620, 622, 623 Dipeptidyl-peptidase-4, 572, 573, 574, 586, 588–589 Diphenhydramine, 842, 853–855 Diphtheria, 274, 279–280 Diphtheria and tetanus toxoids, 279–280 hepatitis B, pertussis, poliomyelitis and Haemophilus influenzae vaccine, 280 hepatitis B, pertussis and poliomyelitis vaccine, 280 pertussis and poliomyelitis vaccine, 280 pertussis vaccine, 280 Dipyridamole, 755, 758 Disopyramide, 702 Disseminated intravascular coagulation (DIC), 760 Distribution, 15, 22–23 drug–drug or drug–alternative therapy interactions, 28 Dithranol, 951 Diuretic agents, 658, 675, 803–816 adults, 806 carbonic anhydrase inhibitors, 805, 809, 811, 813 care considerations, 815–816 children, 806 high-ceiling, 803, 809 loop diuretics, 805, 809–811 older adults, 807 osmotic diuretics, 806, 809, 814–15 potassium-sparing diuretics, 806, 809, 813–814 thiazide and thiazide-like diuretics, 803, 805, 807–809 Diurnal rhythm, 512, 516, 536, 537 Dobutamine, 456, 458, 676

duration of effect, 539 glucose regulation, 575 older adults, 540 routes of administration, 544 transplant care, 268–269 Corticotropin-releasing hormone (CRH), 522–524 Cortisone, 539, 542, 543, 547 Cost considerations, 60, 65–66 Cough, 834, 836 Countercurrent mechanism, 794, 797–798 COX-1 (cyclooxygenase-1), 246, 249 COX-2 (cyclooxygenase-2), 246–250 Coxiella burnetii (Q fever) vaccine, 279 Cranial nerves, 298 Creatine, 632, 964 Cretinism, 551, 555 CRH. See Corticotrophin-releasing hormone (CRH) Crotamiton, 952 Culture, 81, 85 Cumulation drug effects and, 25, 27 Cyanocobalamin, 787, 788 Cyclooxygenase-2 inhibitors, 240 Cyclopentolate, 501, 503, 957 Cyclophosphamide, 195, 196, 198 Cycloplegia, 501, 502 Cyclosporin, 258, 260, 263–265, 268–269 Cyproheptadine, 852, 854 Cystic fibrosis, 834, 839 Cystitis, 819, 820 interstitial, 819, 827 treatment, education regarding, 822–823 Cytarabine, 200, 201, 203 Cytochrome P450, 23 Cytomegalovirus. See Herpes and cytomegalovirus Cytotoxic reaction, 33, 34 Cytotoxic T cells, 233 D Dabigatran, 756, 759–760 Dacarbazine, 195, 196 Dactinomycin, 205 Dalteparin, 195, 757–766 Dantrolene, 385, 386, 390–392, 423 Dapagliflozin, 587, 588, 589–590 Dapsone, 118, 119 Daptomycin, 121 Darbepoetin alfa, 777–780 Darifenacin, 824, 825 Darunavir, 136, 139 Daunorubicin, 205, 206 DAW (dispensed as written), 10 Damiana, 632 Danazol, 629 Dandelion root, 582, 964

Docetaxel, 209 Docusate, 920 Dolasetron, 931, 934 Dolour, 228, 232 Domperidone, 931, 934 Donepezil, 487, 492–496 Dong quai, 613

Dicloxacillin, 108, 109 Didanosine, 136, 137 Diffusion, 72, 76–77 facilitated, 77 Digestion, 891

Dopamine, 297, 455–456, 458–459, 676 dopamine D2 receptor antagonists, 934 Dopaminergic agents, 372, 374–378 adverse effects, 376 care considerations, 377