McKenna's Pharmacology for Nursing, 2e
961
A P P E N D I X E Vitamins
■■ TABLE E Vitamins (continued) Vitamin
Solubility type
Recommended dietary intake (RDI) Therapeutic uses/special considerations
phytonadione (vitamin K)
Fat
70 mcg (male) 60 mcg (female) 60 mcg (breastfeeding) 60 mcg (pregnancy) 25–55 mcg (paediatric) 1.3–1.7 mg (male) 1.3–1.5 mg (female) 2.0 mg (breastfeeding) 1.9 mg (pregnancy) 0.5–1.2 mg (paediatric) 1.3–1.6 mg (male) 1.1–1.3 mg (female) 1.6 mg (breastfeeding) 1.4 mg (pregnancy) 0.5–1.1 mg (paediatric) 1.2 mg (male) 1.1 mg (female) 1.4 mg (breastfeeding) 1.4 mg (pregnancy) 0.5–1.1 mg (paediatric)
Hypoprothrombinaemia due to anticoagulant use: 2.5–10 mg PO, IM. Haemorrhagic disease of the newborn: 1 mg IM within 1 hour of birth. Hypoprothrombinaemia in adult: 2.5–25 mg PO or IM Deficiency: 10–20 mg/day PO or IM for 3 weeks. Vitamin B6 deficiency syndrome: up to 600 mg/day for life
pyridoxine HCl (vitamin B 6
Water
) (Pyroxin)
riboflavin (vitamin B 2 ) (contained in combined generic products)
Water
Treatment of deficiency: 5–15 mg/day. May cause a yellow or orange discolouration to the urine
thiamin (vitamin B 1 ) (B-Dose, Betamin)
Water
Treatment of beriberi: 10–20 mg IM t.d.s. for 2 weeks with multivitamin containing 5–10 mg/day for 1 month. Do not mix in alkaline solutions. Used orally as a mosquito repellent, alters body sweat composition. Feeling of warmth and flushing may occur with administration but usually passes within 2 hours
Reference: National Health and Medical Research Council (2006). Nutrient Reference Values for Australia and New Zealand Including Recommended Dietary Intakes. Commonwealth of Australia, Canberra (currently under review).
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