McKenna's Drug Handbook for Nursing & Midwifery, 7e

Diagnostic preparations     1307

and in investigations of the female genitalia in suspected or confirmed pregnancy. care considerations • Closelymonitorindividualfordevelopment of anaphylactic reaction. Ensure emergency management equipment is available and in correct working order. • Monitor vital signs and renal function closely following procedure. • Ensure the person is well-hydrated before and after the procedure to avoid contrast- • Ensure safety if the person is light-headed. • Thyroid function testsmay be reduced for up to several weeks. Patient teaching • Advise person to report any adverse effects. • Advise person to take care when standing up or getting out of bed due to potential dizziness. induced nephropathy. • Assess mental status.

Route Onset

Peak

Duration

IV

Immediate Unknown 96 hrs

Adverse reactions CNS: abnormal coordination, convulsions , dizziness,drymouth,EEGchanges,headache, hypaesthesia, meningismus, meningitis, nervousness, neuropathy, paraplegia, paraesthesia, somnolence, syncope. CV: anginapectoris,arrhythmia,bradycardia, cardiac arrest , circulatory collapse , dis­ seminated intravascular coagulation , ECG changes, hypertension, hypotension, myocardial ischaemia , palpitations, thrombophlebitis, ventricular and supra­ ventricular ectopic beats, ventricular fibrillation . ENT: nasal congestion, rhinitis, sneezing. Eye: altered vision, blindness, conjunctivitis, eye disorder, itchiness, mydriasis, oculogyric crisis, periorbital oedema. photophobia. GI: abdominal pain, anorexia, diarrhoea, dysphagia, nausea, rectal haemorrhage, vomiting. GU: acuterenalfailure ,alteredrenalfunction contrast medium–induced nephrotoxicity , incontinence, urinary retention. Musculoskeletal: asthenia, muscle cramps, myalgia, myopathy. Psychiatric: agitation, amnesia, confusion. Respiratory: asthma, bronchospasm , dyspnoea, laryngeal oedema , pharyngitis, pulmonary oedema, respiratory distress. Skin: angio-oedema ,clamminess,erythema, flushing, injection site pain, itching, pruritus, rash, sweating, urticaria. Other: anaphylactic reaction, fever, hyper­ sensitivityreactions, iodism,malaise,pyrexia, rigors. Interactions Drug-drug. Metformin/biguanides: Potential transient impairment of renal function with possible lactic acidosis. Should be discontinued 48 hours prior to and for 48 hours after procedure. Interleukin-2: Increased risk of delayed reactions. Monitor closely.

iopamidol Isovue Pregnancy risk category B3 Use in sport: Permitted Available forms

Solution for injection: 200 mg iodine/mL in 10 mL, 20 mL, 50 mL; 300 mg iodine/ mL in 10 mL, 20 mL, 50 mL, 70 mL, 100 mL; 370 mg iodine/mL in 20 mL, 30 mL, 50 mL, 70 mL, 100 mL, 150 mL, 200 mL

Indications & dosages ➤ X-rayorCTcontrastmedium—

Adults: Individualised according to individual factors and nature of X-ray or CT scan. Action Non-ionic iodinated radiographic contrast medium for vascular systems.