Taylor_Speroff's Clinical Gynecologic Endocrinology and Infe

Chapter 8 • Normal and Abnormal Sexual Development 263

Bipotential Stage

Genital tubercle

Urethral folds Labioscrotal swelling

Urogenital slit

Anal pit

Tail

Female

Male

Glans

Genital tubercle

Urogenital slit Urethral folds Labioscrotal swelling

II

Anus

Meatus

Glans penis

Clitoris

Urethral meatus Labia minora Vaginal orifice Labia majora Scrotum Raphe

FIGURE 8.7

pseudohermaphrodite has testes, but a female genital phe notype, and a female pseudohermaphrodite has ovaries, but masculine genital characteristics. However, recent advances in molecular genetic diagnosis and increasing awareness of ethical issues and patient advocacy concerns suggested the need to reexamine the traditional classification scheme and to retire gender-based terms that many now consider pejorative. Ideally, a classification system must be flexible, to allow incorporation of new information, logical, to maintain a

DISORDERS OF SEXUAL DEVELOPMENT

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Disorders of sexual development (DSD) are congenital conditions characterized by atypical development of chro mosomal, gonadal, or phenotypic sex. Traditionally, they have been classified according to gonadal sex. A true her maphrodite has both ovarian and testicular tissue. A male