Rosen's Breast Pathology, 4e

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Chapter 11

FIG. 11.33.  DCIS, “healing.” A: Prominent periductal fibrosis and chronic inflammation. B,C: Severe periductal fibrosis with lymphocytic reaction. The epithelial element is relatively attenuated (C) . D: Scar composed of collagen and elastin fibers with calcifications at the site of “healed” DCIS. ­Images (A–D) are from a single specimen. E: Marked periductal fibrosis with residual necrotic DCIS. F: Concentric fibrosis forms a dense calcified scar with sclerosing entrapment of carcinoma cells. Note periductal lymphovascular channel involvement by tumor cells. No invasive carcinoma was ­identified elsewhere in this case.