Renal Pathophysiology

Contents

Preface iv CHAPTER 1 CHAPTER 2 CHAPTER 3

Overview of Renal Physiology 1

Regulation of Salt and Water Balance 33

Disorders of Water Balance: Hyponatremia, Hypernatremia, and Polyuria 71 Edematous Conditions and the Use of Diuretics 102 Acid-Base Physiology and Metabolic Alkalosis 130

CHAPTER 4

CHAPTER 5

CHAPTER 6 CHAPTER 7 CHAPTER 8

Metabolic Acidosis 160

Disorders of Potassium Balance 182

Urinalysis and Approach to the Patient With Renal Dysfunction 205 Pathogenesis of Major Glomerular and Vascular Diseases 225

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