Non-Neoplastic Dermatopathology

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5.11 Calciphylaxis vs Monckeberg Medial Calcific Sclerosis

Figure 5.11.1 Calciphylaxis. Ischemic necrosis of superficial epidermis with ghost-like outlines of nuclei and pyknosis.

Figure 5.11.2 Calciphylaxis. Vascular congestion and thrombosis with necrosis of fat lobules and septae.

Figure 5.11.3 Calciphylaxis. Mural calcification of small capillaries within subcutaneous adipose tissue. There is vascular congestion and thrombus formation (arrow) with erythrocyte extravasation.

Figure 5.11.4 Calciphylaxis. Plate-like calcifications within the walls of small capillaries in subcutaneous fat lobules. There is surrounding fat necrosis.

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SUBCUTIS

5 DISORDERS OF THE

Figure 5.11.5 Monckeberg medial calcific sclerosis. Calcification in the tunica media of medium-sized arteries within the subcutis. Note that there is no associated fat necrosis.

Figure 5.11.6 Monckeberg medial calcific sclerosis. Calcification in the tunica media of a medium-sized vessel with intimal thickening but no occlusion of the lumen. The erythrocyte extravasation is procedural.