Non-Neoplastic Dermatopathology

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5.6 Eosinophilic Fasciitis vs Scleroderma

Figure 5.6.5 Scleroderma. Sclerotic collagen expanding the reticular dermis and extending into the subcutis along septae.

Figure 5.6.6 Scleroderma. Sclerotic collagen bundles appearing swollen and smudgy with loss of intervening fenestrations. Sclerosis obliterates the subcutaneous adipose tissue but does not extend into the fascia.

Figure 5.6.7 Scleroderma. Sclerotic collagen of reticular dermis encroaching upon the eccrine unit and replacing the normal cuff of fat surrounding the eccrine unit.

Figure 5.6.8 Scleroderma. Lymphoplasmacytic infiltrate in the sclerotic collagen of the deep dermis. Note that eosinophils are not present.

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