Non-Neoplastic Dermatopathology

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5 Disorders of the Subcutis

Figure 5.4.1 Lipodermatosclerosis. Fibrosis and thickening of subcutaneous septae with minimal inflammation.

Figure 5.4.2 Lipodermatosclerosis. Lipomembranous fat necrosis characterized by feathery eosinophilic material at the periphery of fat cells and fat microcysts.

Figure 5.4.3 Lipodermatosclerosis. Lipophagic fat necrosis within the fat lobules with foamy, xanthomatous histiocytes surrounding fat cells of varying size.

Figure 5.4.4 Lipodermatosclerosis. Siderophages (hemosiderin-laden macrophages) within the septae as highlighted with iron stain.

Figure 5.4.6 Traumatic panniculitis. Fat necrosis with formation of fat microcysts of varying size. Septae and lobules are distorted by hyalinized sclerosis. No significant inflammation. Copyright © Wolters Kluwer, Inc. Unauthorized reproduction of the content is prohibited. 2023

Figure 5.4.5 Lipodermatosclerosis. Features of chronic venous stasis within the superficial dermis with grouped, thick-walled vessels.