NPA Q2 2022

MEDICAL Public Health

Designing Clinical Research 5th Edition By Warren S. Browner , Thomas B. Newman , Steven R. Cummings , Deborah G. Grady , Alison J. Huang , Alka M. Kanaya , and Mark J. Pletcher DESCRIPTION For more than 30 years, Designing Clinical Research has set the standard as the most practical, authoritative guide for physi- cians, nurses, pharmacists, and other practitioners involved in all forms of clinical and public health research. Using a reader- friendly writing style, Drs. Warren S. Browner, Thomas B. Newman, Steven R. Cummings, Deborah G. Grady, Alison J. Huang, Alka M. Kanaya, and Mark J. Pletcher, all of the Uni- versity of California, San Francisco, provide up-to-date, com-

monsense approaches to the challenging judgments involved in designing, funding, and implement- ing a study. This state-of-the-art fifth edition features new figures, tables, and design, as well as new editors, new content, and extensively updated references to keep you current. FEATURES ▶ Covers clinical research in its many forms, including clinical trials, observational studies, translational science, and patient-oriented research. ▶ Presents epidemiologic terms and principles and advanced conceptual material in a practical and reader-friendly manner. ▶ Discusses key changes in the field, including confounding and directed acyclic graphs, surrogate outcomes and biomarkers, instrumental variables and Mendelian randomization, regression discontinuity designs, alternative data sources, AI and machine learning, pilot studies, as well as an update on P values and Bayesian analysis.. ▶ Covers modifications of classic randomized trials, such as pre/post, interrupted time series, difference-in-differences, stepped wedge and cluster randomized designs, as well as randomized trials in health systems. ▶ Adds new chapters on qualitative approaches to clinical research and on community-engaged research

ISBN: 978‑1‑9751‑7440‑8 / ($99.99 / £74.00 / €84.00 / AU$153.00) World Approx 468 pp / Approx 50 Tables / 7 x 10 / May 2022

Note to Booksellers: The previous edition published in July 2013 (ISBN: 978-1-60831-804-9)

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