McKenna's Pharmacology for Nursing, 2e

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C H A P T E R 4 1 Drugs affecting the male reproductive system

C H E C K Y O U R U N D E R S T A N D I N G

7. Men taking alprostadil for treatment of erectile dysfunction must: a. take the drug orally about 1 hour before anticipated intercourse. b. arrange for sexual stimulation to promote erection. c. learn to inject the drug directly into the penis. d. avoid the use of nitrates for cardiovascular disorders. 8. Viagra is known to: a. cause unexpected and enlarged erections. b. make a person young and agile. c. promote interpersonal relationships between partners. d. increase nitrous oxide levels in the corpus

Answers to the questions in this chapter can be found in Appendix A at the back of this book.

MULTIPLE CHOICE Select the best answer to the following. 1. Testosterone is approved for use in: a. treatment of breast cancers. b. increasing muscle strength in athletes. c. oral contraceptives. d. increasing hair distribution in male pattern baldness. 2. Illegal use of large quantities of unprescribed anabolic steroids to enhance athletic performance has been associated with: a. increased sexual prowess. b. muscle rupture from overexpansion. c. development of chronic obstructive pulmonary disease (COPD). d. cardiomyopathy and liver cancers. 3. Anabolic steroids would be indicated for the treatment of: a. hair loss b. angio-oedema. c. debilitation and severe weight loss. d. breast cancers in males. 4. Erectile penile dysfunction is a condition in which: a. problems with childhood authority figures prevent a male erection. b. the corpus cavernosum does not fill with blood to allow for penile erection. c. the sympathetic nervous system fails to function. d. past exposure to sexually transmitted infections causes physical damage within the penis. 5. A potentially deadly drug–drug interaction can occur if a PDE5 inhibitor (sildenafil, tadalafil or vardenafil) is combined with: a. corticosteroids. b. oral contraceptives. c. organic nitrates. d. halothane anaesthetics. 6. To achieve erection, a person taking sildenafil ( Viagra ) would require: a. sexual stimulation of the penis. b. no additional stimulation. c. privacy. d. 10 to 15 minutes after taking the oral drug.

cavernosum, causing vascular relaxation and promoting blood flow into the corpus cavernosum.

MULTIPLE RESPONSE Select all that apply. 1. In assessing a person for androgenic effects, you would expect to find which of the following? a. hirsutism

b. deepening of the voice c. testicular enlargement d. acne e. elevated body temperature f. sudden growth

2. A child treated with anabolic steroids because of anaemia associated with renal disease will need: a. early sex education classes because of the effects of the drug. b. X-rays of the long bones every 3 to 6 months so the drug can be stopped when the bone size is appropriate to the child’s age. c. to learn to shave. d. to learn to cope with an altered body image. e. regular monitoring of liver function tests. f. monitoring for the development of oedema.