McKenna's Pharmacology for Nursing, 2e

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C H A P T E R 3 5 Hypothalamic and pituitary agents

C H E C K Y O U R U N D E R S T A N D I N G

7. Treatment with ADH preparations is associated with adverse effects, including: a. constipation and paralytic ileus. b. cholecystitis and bile obstruction. c. nocturia and bed wetting. d. “hangover” symptoms, including headache, sweating and tremors. 8. A person who is receiving an ADH preparation for diabetes insipidus may need instruction in administering the drug: a. orally or intramuscularly. b. orally or intranasally. c. rectally or orally. d. intranasally or by dermal patch. 1. Octreotide ( Sandostatin ) would be the drug of choice in the treatment of acromegaly in a person with which of the following conditions? a. diabetes b. gallbladder disease c. adrenal insufficiency d. hypothalamic lesions e. intolerance to other therapies f. acromegaly in a person older than the age of 18 years 2. A father brought his 15-year-old son to the endocrine clinic because the boy was only 152 centimetres tall. He wanted his son to receive growth hormone therapy because short stature would be a detriment to his success as an adult. The boy would be considered for this therapy under which of the following circumstances? a. If he were against the use of cadaver parts. MULTIPLE RESPONSE Select all that apply.

Answers to the questions in this chapter can be found in Appendix A at the back of this book.

MULTIPLE CHOICE Select the best answer to the following.

1. Hypothalamic hormones are normally present in very small amounts. When used therapeutically, their main indication is: a. diagnosis of endocrine disorders and treatment of specific cancers. b. treatment of multiple endocrine disorders. c. treatment of CNS-related abnormalities. d. treatment of autoimmune-related problems. 2. Somatropin ( Genotropin and others) is a genetically engineered growth hormone that is used: a. to diagnose hypothalamic failure. b. to treat precocious puberty. c. in the treatment of children with growth failure. d. to stimulate pituitary response. 3. Growth hormone deficiencies: a. occur only in children. b. always result in dwarfism. c. are treated only in children because GH is usually produced only until puberty. a. a bowel program to deal with constipation. b. tests for thyroid function and glucose tolerance. c. a kilojoule check to control weight gain. d. tests of adrenal hormone levels. 5. Acromegaly and gigantism are both conditions related to excessive secretion of: a. thyroid hormone. b. melanin-stimulating hormone. c. growth hormone. d. oxytocin. 6. Diabetes insipidus is a relatively rare disease characterised by: a. excessive secretion of ADH. b. renal damage. c. the production of large amounts of dilute urine containing no glucose. d. insufficient pancreatic activity. d. can occur in adults as well as children. 4. People who are receiving growth hormone replacement therapy must be monitored very closely. Routine follow-up examinations would include:

b. If his epiphyses were closed. c. If his GH levels were very low. d. If he were also diabetic. e. If he had chronic renal failure. f. If he had hypothyroidism.