McKenna's Pharmacology for Nursing, 2e

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P A R T 5  Drugs acting on the autonomic nervous system

Wiysonge, C. S. & Opie, L. H. (2013). b -blockers as initial therapy for hypertension. JAMA , 310(7) , 1851?1852. Wiysonge, C. S., Bradley, H. A, Volmink, J., Mayosi, B. M., Mbewu, A. & Opie, L. H. (2012). Beta-blockers for hypertension. Cochrane Database of Systematic Reviews , CD002003.

O’Donovan, K. (2012). Amiodarone and its role in arrhythmia. Nurse Prescribing , 10(5) , 241–246. Porth, C. M. (2011). Essentials of Pathophysiology: Concepts of Altered Health States (3rd edn). Philadelphia: Lippincott Williams & Wilkins. Porth, C. M. (2009). Pathophysiology: Concepts of Altered Health States (8th edn). Philadelphia: Lippincott Williams & Wilkins.

C H E C K Y O U R U N D E R S T A N D I N G

Answers to the questions in this chapter can be found in Appendix A at the back of this book.

6. A nurse or midwife would question an order for beta 1 -selective adrenergic blocker for a person with: a. cardiac arrhythmias. b. hypertension. c. cardiogenic shock. d. open-angle glaucoma. 7. A smoker who is being treated for hypertension with a beta-blocker is most likely receiving: a. a non-specific beta-blocker. b. an alpha 1 -specific beta-blocker. c. beta- and alpha-blockers. d. a beta 1 -specific blocker. 8. You would caution a person who is taking an adrenergic blocker: a. to avoid exposure to infection. b. to stop the drug if they experience flu-like symptoms. 1. A nurse or midwife would question an order for a beta-adrenergic blocker if the person was also receiving what other drugs? a. clonidine b. ergot alkaloids c. aspirin d. NSAIDs e. triptans f. adrenaline 2. The beta-adrenergic blocker propranolol is approved for a wide variety of uses. Which of the following are approved indications? a. migraine headaches b. stage fright c. bronchospasm d. reinfarction after an MI e. erectile dysfunction f. hypertension c. never to stop the drug abruptly. d. to avoid exposure to the sun. MULTIPLE RESPONSE Select all that apply.

MULTIPLE CHOICE Select the best answer to the following. 1. Adrenergic blocking drugs, because of their clinical effects, are also known as: a. anticholinergics. b. sympathomimetics. c. parasympatholytics. d. sympatholytics. 2. The nurse or midwife would anticipate administering drugs that generally block all adrenergic receptor sites to treat: a. allergic rhinitis. b. COPD. c. cardiac-related conditions. d. premature labour. 3. Phentolamine ( Regitine ), an alpha-adrenergic blocker, is most frequently used: a. to prevent cell death after extravasation of intravenous dopamine or noradrenaline. b. to treat COPD in people with hypertension or arrhythmias. c. to treat hypertension and BPH in males. d. to block bronchoconstriction during acute asthma attacks. 4. A person with which of the following would most likely be prescribed an alpha1-selective adrenergic blocking agent? a. COPD and hypotension b. hypertension and BPH c. erectile dysfunction and hypotension d. shock states and bronchospasm 5. The beta-blocker of choice for a person who is hypertensive and has angina is:

a. nebivolol. b. pindolol. c. timolol. d. sotolol.