McKenna's Pharmacology for Nursing, 2e

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C H A P T E R 1 7  Immune modulators

C H E C K Y O U R U N D E R S T A N D I N G

5. You might use a monoclonal antibody in treating: a. warts. b. herpes zoster. c. tumours that overexpress HER2. d. Kaposi’s sarcoma.

Answers to the questions in this chapter can be found in Appendix A at the back of this book.

MULTIPLE CHOICE Select the best answer to the following.

1. In which situation would the health professional be least likely to expect to administer an immune suppressant? a. treatment of transplant rejection b. treatment of autoimmune disease c. reduction of number of relapses in multiple sclerosis d. treatment of aggressive cancers 2. Teaching for an individual receiving an interferon would include: a. proper use of oral contraceptives. 3. People who are receiving an immune stimulant may experience any of the clinical signs of immune response activity, including: a. flu-like symptoms. b. diarrhoea. c. constipation. d. headache. 4. Organ transplants are often rejected by the body because the T cells recognise the transplanted cells as foreign and try to destroy them. Treatment with b. use of aspirin to control adverse effects. c. importance of cardiovascular workouts. d. proper methods of injecting the drug.

MULTIPLE RESPONSE Select all that apply.

1. The nurse is assigned to care for a person who is receiving immune suppressants. The nurse would continually assess the person for which of the following anticipated adverse effects?

a. development of cancers b. increased risk of infection c. cardiac standstill d. development of secondary infections e. increased bleeding tendencies f. hepatomegaly

2. Teaching points that the nurse would incorporate into the care of a person receiving cyclosporin would include which of the following? a. Use barrier contraceptives to avoid pregnancy. b. If mouth sores occur, try to restrict eating as much as possible. c. Dilute the solution with milk, chocolate milk, or orange juice and drink immediately. d. Avoid drinking grapefruit juice when on this drug. e. Stop taking the drug if GI upset or fever occurs. f. Refrigerate the oral solution.

an immune suppressant would: a. activate antibody production. b. stimulate interleukin release. c. stimulate thymus secretions. d. block the initial damage to the transplanted cells.