McKenna's Pharmacology for Nursing, 2e

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C H A P T E R 1 0  Antiviral agents

8. Locally active antiviral agents can be used to treat: a. HIV infection. b. warts. c. RSV. d. CMV systemic infections.

4. Herpes viruses cause a broad range of conditions but have not been identified as the causative agent in: a. cold sores. b. shingles. c. genital infections. d. leprosy. 5. Which of the following would be an important teaching point for the person receiving an agent to treat herpes virus or CMV? a. Stop taking the drug as soon as the lesions have disappeared. b. Sexual intercourse is fine—as long as you are taking the drug, you are not contagious. c. Drink plenty of fluids to decrease the drug’s toxic effects on the kidneys. d. There are few if any associated GI adverse effects. 6. HIV selectively enters which of the following cells: a. B clones. b. helper T cells. c. suppressor T cells. d. cytotoxic T cells. 7. Care interventions for the person receiving antiviral drugs for the treatment of HIV probably would include: a. monitoring renal and hepatic function periodically during therapy. b. administering the drugs just once a day to increase drug effectiveness. c. encouraging the person to avoid eating if GI upset is severe. d. stopping the drugs and notifying the prescriber if severe rash occurs.

MULTIPLE RESPONSE Select all that apply.

1. When explaining to a person the reasoning behind using combination therapy in the treatment of HIV, the nurse or midwife would include which of the following points? a. The virus can remain dormant within the T cell for a very long time; they can mutate while in the T cell. b. Adverse effects of many of the drugs used to treat this virus include immunosuppression, so the disease could become worse. c. The drugs are cheaper if used in combination. d. The virus slowly mutates with each generation. e. Attacking the virus at many points in its life cycle has been shown to be most effective. f. Research has shown that using only one type of drug that targeted only one point in the virus life cycle led to more mutations and more difficulty in controlling the disease.