McKenna's Drug Handbook for Nursing & Midwifery, 7e

1302      Miscellaneous drug categories

Musculoskeletal: arthralgia, back pain, nephrogenic systemic fibrosis , pain in extremity. Psychiatric: agitation, confusion, disorien­ tation. Respiratory: bronchospasm , cough, dry throat, dyspnoea, laryngospasm , nasal congestion, pharyngolaryngeal pain, respiratory arrest , respiratory distress , sneezing. Skin: eczema, erythema, pruritus, rash, urticaria. Other: anaphylactic reaction , angio- oedema , asthenia, fatigue, hypersensitivity, injection site pain, malaise. Interactions None reported. Contraindications Contraindicated in individuals with known hypersensitivity to the preparation and in those with pacemakers or vascular clips. care considerations • Increased risk of nephrogenic systemic fibrosis in individuals with acute or chronic renal failure or acute renal insufficiency, or during the perioperative period in liver transplantation. Renal function should be assessed in all individuals prior to the procedure. • Closelymonitor individualfordevelopment of anaphylactic reaction. Ensure emergency management equipment is available and in correct working order. • Monitor vital signs closely following procedure. Patient teaching • Advise person to report any adverse effects.

gadoteridol ProHance Pregnancy risk category B3 Use in sport: Permitted Available forms Vial: 279.3 mg/mL in 15 mL, 20 mL Prefilledsyringe: 279.3mg/mL in10mL,15mL Indications & dosages ➤ EnhancementofCNSorwhole-bodyMRI— Adultsandchildrenover2years: 0.1mmol/ kg bodyweight by IV bolus or infusion. Action Paramagnetic contrast agent used for imaging of intracranial and spinal lesions in presence of abnormal blood–brain barrier or abnormal vascularity, as well as whole-body imaging. Route Onset Peak Duration IV Immediate Unknown 24 hrs Adverse reactions CNS: burning sensation, cold sensation, coma , convulsions , dizziness, headache, seizure, syncope, warm sensation. CV: angina pectoris, arrhythmias, brady­ cardia, cardiac arrest , circulatory collapse , cyanosis, hypertension, hypotension, palpi­ tations, syncope, tachycardia, vasodilation. ENT: deafness. Eye: altered lacrimation, conjunctivitis, eye disorder. GI: abdominal pain, diarrhoea, dysphagia, gingival swelling, mouth oedema, nausea, taste alteration, tongue oedema, vomiting. GU: acute kidney injury , urinary incontin­ ence. Musculoskeletal: arthralgia, back pain, chest pain, nephrogenic systemic fibrosis , pain in extremity. Psychiatric: agitation, confusion, disorien­ tation.

Reactions may be common , uncommon, life-threatening , or commonandlife-threatening.