Kaplan and Sadocks Comprehensive Textbook of Psychiatry, 11e

Contents

About the Editors ............................ vi Contributors .............................. xxiii Preface ................................... lvii Foreword ..................................lix

VOLUME I

1 NEURAL SCIENCES

1.9 Novel Neurotransmitters

124 Thomas W. Sedlak, M.D., Ph.D., Bindu D. Paul, Ph.D., and Adam I. Kaplin, M.D., Ph.D. 140 Jihye Kim, M.D., Francis S. Lee, M.D., Ph.D., and Moses V. Chao, Ph.D.

1 1

1.1 The Neuroscience of Psychiatry John H. Krystal, M.D. 1.2 Functional Neuroanatomy Darlene S. Melchitzky, M.S., and David A. Lewis, M.D. 1.3 Functional Genomics of Human Brain Development

1.10 Neurotrophic Factors

3

1.11 Intraneuronal Signaling John A. Gray, M.D., Ph.D. 1.12 Psychoneuroendocrinology Victor I. Reus, M.D. 1.13 Immune–Brain Interactions in Psychiatry

145

43 Kartik Pattabiraman, M.D., Ph.D., Sirisha Pochareddy, Ph.D., John C. Silbereis, Ph.D., John N. Constantino, M.D., and Nenad Sestan, M.D., Ph.D.

157

171

1.4 Neural Development and Neurogenesis

Ebrahim Haroon, M.D., Andrew H. Miller, M.D., and Charles L. Raison, M.D. 1.14 Chronobiology, Circadian Rhythm, and Psychiatry 194 Chester Wu, M.D., and Joshua J. Rodgers, M.D. 1.15 Basic Science of Sleep 199 Ruth M. Benca, M.D., Ph.D., Chiara Cirelli, M.D., Ph.D., and Giulio Tononi, M.D., Ph.D. 1.16 Pain Systems: Interface with Affective and Motivational Mechanisms 215 John Lotfi, M.D., J.D., and Jon-Kar Zubieta, M.D., Ph.D. 1.17 Basic Science of Appetite 219

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Emanuel DiCicco-Bloom, M.D., and Courtney R. McDermott, B.A. 1.5 Cellular and Synaptic Basis of Neural Signaling Charles F. Zorumski, M.D., and Steven Mennerick, Ph.D. 1.6 Amino Acid Neurotransmitters Joseph T. Coyle, M.D. 1.7 Biogenic Amine Neurotransmitters John D. Elsworth, Ph.D. 1.8 Neuropeptides: Biology, Regulation and Role in Neuropsychiatric Disorders 108 Michael J. Owen, B.Sc. (Hons.), M.B., Ch.B., Ph.D., F.R.C.P.sych., Shaun P. Brothers, Ph.D., M.B.A., Larry J. Young, Ph.D., and Charles B. Nemeroff, M.D., Ph.D. 67 83 93

Nori Geary, Ph.D., and Timothy H. Moran, Ph.D.

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