Chi_Principles and Practice of Gynecologic Oncology 8e

xxiv Contents

10.6

11.11 Multidisciplinary Approach to Breast Cancer Care 530 Theresa A. Graves, Stephanie L. Graff, and Jaroslaw T. Hepel 11.12 Systemic Treatment for Metastatic Breast Cancer 532 Stephanie L. Graff and Mary Anne Fenton 11.13 Breast Cancer in the Older Patient 537 Theresa A. Graves and Mary Anne Fenton 11.14 Pregnancy-Associated Breast Cancer 539 Rani Bansal 11.15 Breast Cancer: Survivorship Issues 543 Christine Duffy and Don S. Dizon Clinical Trials Methodology and Analysis 553 Jeffrey C. Miecznikowski, Austin Miller, and Michael W. Sill Cost-Effective and Value-Based Gynecologic Cancer Care 571 Laura J. Havrilesky, Margaret I. Liang, Emeline M. Aviki, Shalini L. Kulasingam, Elizabeth L. Jewell, and David E. Cohn Nutrition Support of Patients With Gynecologic Cancer 635 Sanjana Luther and Priya K. Simoes Management of Pain 653 Russell K. Portenoy and Ebtesam Ahmed Palliative and Supportive Care 675 Emily J. Martin and Natsai C. Nyakudarika Hereditary Cancer Genetics 688 Catherine Watson and Andrea R. Hagemann Biologic and Physical Principles of Radiation Oncology 696 Jenna Kahn, Beth A. Erickson, Meena Bedi, Firas Mourtada, and Sunil J. Advani 12.2 12.3 Perioperative and Critical Care 590 James J. Burke II, Ashley Valenzuela, and Katherine M. McBride 12.4 12.5 12.6 12.7 12.8 SECTION 12 SPECIAL TOPICS 551 12.1

Therapy for Ovarian Sex Cord-Stromal Tumors: Radiation, Chemotherapy, Targeted Therapy, Immunotherapy, and Other New and Novel

Agents 464 R. Tyler Hillman

10.7 Treatment of Persistent or Recurrent Sex Cord Stromal Tumors 466 R. Tyler Hillman Ovarian Sex Cord-Stromal Tumors: Special Conditions 469 Carrie Langstraat Ovarian Sex Cord-Stromal Tumors: Follow-Up and Survivorship Issues 470 Carrie Langstraat 10.10 Ovarian Sex Cord-Stromal Tumors: Future Directions 470 R. Tyler Hillman 10.8 10.9

SECTION 11 BREAST CANCER 473 11.1

Breast Cancer: Introduction 475 Theresa A. Graves

11.2

Breast Cancer: Epidemiology, Risk Factors, Anatomy, and Natural History 475 Michelle E. Wakeley Breast Cancer: Clinical Presentation 478 Julia Tassinari

11.3

11.4

Breast Imaging 485 Martha B. Mainiero and Robert C. Ward Breast Pathology 490 Yihong Wang and Evgeny Yakirevich

11.5

11.6 Surgical Management of the Breast 502 Doreen L. Wiggins and Theresa A. Graves Surgical Management of the Axilla 507 Charu Taneja Endocrine Therapy for Breast Cancer 512 Mary Anne Fenton Approaches to Systemic Therapy for Breast Cancer: Neoadjuvant and Adjuvant Management 518 Stephanie L. Graff 11.10 Radiation Therapy for Breast Cancer 523 Jaroslaw T. Hepel and Chelsea Miller 11.7 11.8 11.9

Index 751

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